The generic name of this product is Sodium Hyaluronate and the brand name is Euflexxa. It is used to treat patients who are suffering from OA of the knee and those who have not found success with other treatments. This product is a derivative of hyaluronic acid. It increases the efficiency of the fluid so that it works as a shock absorber and lubricant within the knee joint.

Euflexxa is a flexible and elastic substance, which is made from hyaluronan and is a solution of sodium hyaluronate. Hyaluronan is a natural chemical found in the body and is found in the normal joint fluids and is viscous in nature. Euflexxa is a variety of hyaluronates, which is used in viscosupplementation. Viscosupplementation is a form of knee treatment. The procedure of viscosupplementation involves the injection of the hyaluronates into the affected joint to supplement the lacking viscous properties of the synovial fluid in that body joint. Apart from Synvisc, this product is also used in viscosupplementation as an effective therapy.

Treating knee pain in patients with osteoarthritis who have not received relief from other treatments.

This product is a hyaluronic acid derivative. It works by increasing the effectiveness of the fluid within the knee joint to act as a lubricant and shock absorber.

· you are allergic to any ingredient in this product

· you have an infection or skin disease near the joint or injection site

Contact your doctor or health care provider right away if any of these apply to you.

Before using this product:

Some medical conditions may interact with Euflexxa. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

· if you are pregnant, planning to become pregnant, or are breast-feeding

· if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

· if you have allergies to medicines, foods, or other substances

· if you are allergic to birds or bird products (eg, eggs, feathers, poultry)

Some MEDICINES MAY INTERACT with Euflexxa. Tell your health care provider if you are taking any other medicines, especially any of the following:

· Quaternary ammonium salts because side effects may occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Euflexxa may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use this product:

Check the label on the medicine for exact dosing instructions.

· This product comes with an additional patient leaflet. Read it carefully and reread it each time you get Euflexxa refilled.

· Euflexxa is usually administered as an injection at your doctor's office, hospital, or clinic.

· This product is usually given as a series of injections 1 week apart for a total of 3 to 5 injections depending upon the particular product you are using. You may not experience relief until you have received several injections.

· If Euflexxa contains particles or is discolored, or if the vial is cracked or damaged in any way, do not use it.

· Do not use disinfectants containing ammonium salts to prepare the skin for injection because side effects may occur.

· Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Dispose of properly after use. Ask your doctor or pharmacist to explain local regulations for proper disposal.

· If you miss a dose of Euflexxa, contact your doctor to establish a new dosing schedule.

Important safety information about Euflexxa:

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· You may experience a temporary inflammation in your knee after using this product. If the inflammation is severe or continues, contact your doctor.

· Avoid strenuous activity or prolonged (more than 1 hour) weight-bearing activity (eg, running, tennis, heavy lifting) for at least 48 hours after you are injected with this product.

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· PREGNANCY and BREAST-FEEDING: If you become pregnant while using this product, discuss with your doctor the benefits and risks of using this product during pregnancy. It is unknown if Euflexxa is excreted in breast milk. If you are or will be breast-feeding while you are using this product, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Euflexxa:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Back pain; mild bruising, heat, redness, swelling, or pain at the injection site; temporary achy feeling; temporary knee inflammation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

Proper storage of this product:

This product is usually handled and stored by a health care provider.

*We sell only genuine Euflexxa products from Europe that are manufactured by Ferring.

Some products may look slightly different than in the pictures shown on our site. Some products may have some foreign language on it depending on its country of origin. However, most products have predominantly English language packaging.

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